Amoxicillin Injection 20%
Pharmacodynamics: Amoxicillin belongs to β -lactam antibacterial drugs, with a broad spectrum of antibacterial action. Antibacterial spectrum and antibacterial activity and ampicillin are basically the same, most of the gram-positive bacteria antibacterial activity is slightly weaker than penicillin, penicillin enzyme sensitive, so penicillin resistant staphylococcus aureus ineffective. It has a strong effect on gram-negative bacteria, such as Escherichia coli, Proteus, Salmonella, haemophilus, Brucella and Pasteurella, but these bacteria are prone to drug resistance. Not sensitive to Pseudomonas aeruginosa. Because its absorption in monogastric animals is better than that of diampicillin and its blood concentration is higher, it has a better effect on systemic infection. Applicable to respiratory system, urinary system, skin and soft tissue infection caused by sensitive bacteria.
Pharmacokinetics Amoxicillin is fairly stable to gastric acid, with absorption of 74% to 92% in monogastric animals after oral administration. Gastrointestinal tract contents affect the absorption rate, but not the degree of absorption, so it can be mixed. After the same dose of oral administration, the serum concentration of amoxicillin is 1.5-3 times higher than ampicillin.
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